Just days after Google launched its list of healthtech startups for its AI x EMEA accelerator, the Mayo Clinic announced the 15 startups selected for its Mayo Clinic Platform_Accelerate program.
These early-stage companies from around the world are using AI to solve real clinical challenges and change how healthcare is delivered.
“We are incredibly proud to celebrate these 15 companies. Their dedication and accomplishments have raised the bar, and we look forward to continuing to support their efforts as they make strides in advancing patient care worldwide.”
–Jamie Sundsbak, Senior Manager of Mayo Clinic Platform_Accelerate.
The program aims to help startups validate and prepare AI-powered solutions for real-world clinical use. Read on to know how these startups are making a difference.
What Mayo Clinic’s list indicates
Thomas Hagemeijer, founder of HGM Advisory, analysed these 15 startups and here’s what he notes:
A strong focus on clinical and preventive AI
Unlike many accelerators that support a broad range of HealthTech innovations—from billing automation to virtual wellness—Mayo Clinic is laser-focused on clinical AI. Almost all the selected startups are working on tools designed to directly improve patient care.
Even more notable is Mayo’s emphasis on preventive and predictive health. Seven of the 15 companies are building technologies that can catch health problems early, before they become serious. This is an exciting direction that aligns with global healthcare’s shift from treatment to prevention.
Spotlight on Japan’s rising healthtech scene
Four of the 15 companies selected are from Japan—a surprising number given the country’s relatively quiet presence in the global HealthTech scene. Until now, countries like India, Singapore, and China have received most of the attention for AI in healthcare across Asia.
Mayo Clinic’s selection spotlights Japan’s emerging ecosystem and signals that the country may soon be a bigger player in AI HealthTech innovation.
Women’s health gets the attention it deserves
Startups focused on women’s health are also well-represented in this year’s cohort. This is part of a broader trend in the industry. Many companies are working on highly specialised solutions for problems like menopause, pelvic pain, or fertility.
Spotlight on the 2025 cohort
The new cohort of 15 startups recently showcased their work at a demo day event in Eagan, Minnesota. Here’s a quick look at what a few of them are building:
It has developed a hands-free, AI-powered ultrasound device that allows any user to quickly scan for heart and lung issues in children. This device can even work in remote or low-resource settings.
An AI platform that tracks alcohol use and helps prevent liver disease.
Uses AI to fix common problems in clinical trials, like delays and recruitment challenges.
Builds AI tools to diagnose and manage pelvic pain disorders in women.
OPTT:
A mental health platform helping clinicians use data to make better decisions and personalise care.
Addie is an AI assistant that helps hospitals identify patients ready for post-acute care and makes the transition smoother between hospital and recovery settings.
PONS:
Enhances ultrasound imaging using AI, improving resolution and clarity without expensive hardware upgrades, making scans more accurate and accessible.
Uses AI to continuously monitor respiratory data from patient records, helping detect and manage breathing-related health conditions early.
Improves breast cancer detection with AI-enhanced ultrasounds, especially helpful for women with dense breast tissue, reducing missed diagnoses and false alarms.
Focuses on early diagnosis and behavioural support for brain disorders like dementia and depression, using AI to help ageing populations manage cognitive decline.
An AI-powered symptom checker used by millions that helps people get to the right care faster and supports clinics in offering better treatment based on patient inputs.
Developing a machine-learning tool that predicts life-threatening complications in patients with complex heart and aortic conditions, helping doctors act before it’s too late.
Combines hospital and home-based data to monitor how well treatments work in real time, helping improve care decisions and patient safety.
An AI app for women over 35 that provides personalised support around menopause. It raises awareness, guides diagnosis, and offers evidence-based care tips.
Offers an AI tool that simplifies data analysis for healthcare teams. It aims to make it easier to pull meaningful insights from large datasets without advanced technical skills.
How the Mayo Clinic will assist these startups
Mayo Clinic gives the selected startups access to real-world (but de-identified) clinical data and powerful tools to test and validate their ideas.
They also get hands-on guidance from experts on things like regulations, clinical workflows, tech development, and business strategy.
The goal is to help budding healthtech startups fine-tune their solutions, get ready for the market, and connect with investors and healthcare leaders.
Mayo Clinic making a difference
Mayo Clinic is known as the world’s top hospital for a reason. With programs like Platform_Accelerate and Mayo Clinic Ventures, they’re not just providing care, they’re also acting as an accelerator and investor, helping to shape the future of healthcare innovation.
Since 2022, the Mayo Clinic Platform_Accelerate program has welcomed over 45 startups, while Mayo Clinic Ventures has invested in more than 100. It’s their way of supporting new ideas and bringing cutting-edge health tech to life.
Why it matters
The global AI healthcare market is on track to hit $164.16 billion by 2030, and AI startups are playing a major role in this growth. Programs like Mayo Clinic Platform_Accelerate help these startups stay on the right path by offering expert mentorship, medical data access, and real-world guidance.
This kind of support ensures AI tools are safe, effective, and truly useful in healthcare. As more hospitals look to combine technology with patient care, Mayo Clinic’s model shows how to build a smarter, more efficient healthcare system—one innovation at a time.
-By Rinkle Dudhani and the AHT Team.
