HLTH isn’t just another healthtech conference. It is the world’s biggest healthtech event, the stage for global health innovation. And the 2025 gathering didn’t disappoint!
Held in Las Vegas from Oct 19 to 22, HLTH 2025 brought together over 12,000 leaders, hundreds of startups, and the biggest names in tech, policy, and care delivery.
Over four packed days, there were 60+ major announcements, 40+ new partnerships, and dozens of innovators recognized for transforming care. Major reports were launched, startups were crowned, and bold ideas became blueprints for change.
Here’s a complete recap of everything that happened at HLTH USA 2025.
Key sessions, discussions, and takeaways
This year, discussions at HLTH revolved around how healthcare is moving from fragmented to connected, from reactive to predictive, and from system-centered to human-centered.
The patient as CEO: Empowering vs. overwhelming
One question that echoed across sessions is, Are we empowering patients, or simply overwhelming them?
On the “The Bigger Picture: Scaling Personalized Medicine for All” panel, Margaret Anderson of Deloitte reframed the issue with a pointed question:
“The consumer is the ultimate CEO of their health, but are we putting more burden on the patient than we should be?”
Her comment highlighted the fine line between empowerment and overload.
Oura CEO Tom Hale added perspective, highlighting the limitations of traditional medicine in disease prevention:
“There simply aren’t enough doctors or days or communication pathways to change your behavior.”
He sees responsible wearables as the solution. Data-driven tools with “rigorous, responsible FDA collaboration” to make preventive care personal and evidence-based.
Disrupting healthcare: Transparency, affordability, and accountability
Entrepreneur and investor Mark Cuban took the main stage alongside Zach Stafford of SiriusXM, delivering a blunt call to disrupt healthcare.
He demanded action, pushing for transparency, lower costs, and patient-first access. He proposed using technology and entrepreneurial drive to cut costs and put individuals in charge of their health.
Echoing the sentiment, Tilak Mandadi of CVS Health summed it up bluntly:
“Healthcare is horribly broken…We need to redesign it and rebuild it.”
This urgency was echoed by Calley Means and Emily Kumler Kaplan, who championed the Make America Healthy Alliance (MAHA) as a model for uniting policy, innovation, and local action to drive reform.
The AI revolution: From theory to immediate impact
At HLTH USA 2025, AI was consistently emphasised as a present force in healthcare transformation.
Google Cloud’s Francis deSouza championed AI’s power to accelerate research and humanize care. He spotlighted a massive failure and opportunity:
“97% of healthcare data goes unused.”
For AI to succeed, he called for a new model. It must be built on strong data governance, cross-industry collaboration, and a human-centered approach.
A roundtable by Eolas Medical reinforced that AI must work for clinicians, not add to their burden. When designed with care, AI can amplify clinical judgement and free up doctors’ time to focus on the patient.
Advancing women’s health: Bridging disparities and investment
A significant portion of the main stage dialogue was dedicated to spotlighting the power of research, representation, and care models that center on women.
HLTH 2025 was about finally giving women’s health the attention and funding it deserves.
Dr. Jessica Shepherd of hims & hers issued a powerful correction:
“Women’s health shouldn’t be women’s health, it should be health.”
She argued that bridging disparities at all levels is the only path to true equity in care.
Jessica Federer, Lucy Perez, Tracy Warren, and Basmah Safdar unveiled The Women’s Health Fund, calling out decades of neglect in research and investment.
“We didn’t include women in clinical trials in the U.S. till 1993… We owe women decades of scientific advancement, and it’s time to deliver.”
The Women’s Health Fund is a new life-sciences “fund of funds” that aims to activate $60 billion in capital and systematically build the infrastructure, research ecosystems, and market pipelines long overdue for women’s health.
The human side of innovation: Hope and clinical trials
Hollywood icon and advocate Rob Lowe joined cancer clinical trial participant Alicia Dellario and Jacob Van Naarden of Lilly Oncology to share personal stories about hope and healing in research.
Rob Lowe highlighted a new era of public education:
“There’s no reason that we all can’t be educated in ways that would have been unimaginable even five years ago.”
Their discussion reframed clinical trials not as experiments, but as pathways to care and discovery. Yet, with only 7% of U.S. cancer patients enrolling, the call for awareness remains strong.
Other key themes and sessions
- Connected care: Leaders tackled the challenge of integrating fragmented data. They stressed the need to make remote patient monitoring seamless, secure, and scalable within clinical workflows.
- Nurse-led innovation: A NurseHackathon proved the power of frontline insight. By developing 15 solutions in under two hours, Nurses demonstrated they will “change the world when given the opportunity to innovate.”
- Focus on prevention: Experts agreed that sustainable health outcomes depend on uniting food, tech, and medicine as one ecosystem.
- Design for all: Shelley Zalis championed equitable design, stating: “If we design the system with everyone in mind, it will work for everyone.”
Key launches and announcements at HLTH 2025
HLTH USA 2025’s show floor and stages buzzed with new launches, tools, and technologies that promise to reshape care.
AI-driven solutions
- GE HealthCare introduced Agentic AI for Radiology, embedding diagnostic AI assistants directly into imaging devices.
- Atropos Health & Microsoft launched an AI Evidence Agent at Stanford to generate patient-specific, real-world insights right inside EHRs.
- Suki expanded its ambient AI to automatically generate billing codes from clinical conversations.
- Cedar unveiled an AI-driven tool that simplifies Medicaid enrollment for hospitals.
Prevention and consumer health tools
- Noom rolled out free AI-powered health tools, including a Face Scan that turns a selfie into a vital signs snapshot.
- Podimetrics debuted SmartMat+, an in-home device that remotely detects early signs of foot ulcers and fall risks.
AI for clinical operations
- The American Medical Association launched its Center for Digital Health and AI for physicians to participate and lead AI development and deployment.
- Martlet.ai introduced a platform automating Medicare Advantage RADV audits.
- WestCX launched an Agentic AI system that automates 80% of standard pharmacy inquiries.
Strategic partnerships at HLTH USA 2025
If there was one takeaway from HLTH 2025, it’s this: partnerships are healthcare’s new power source.
Data & infrastructure collaborations
- Google Cloud + InterSystems announced a FHIR-ready data foundation to break down healthcare’s data silos.
- Oracle Health + Baylor College of Medicine joined forces to use AI on 120M+ patient records to tackle alcohol-related liver disease.
- Altera + Health Gorilla unveiled Sunrise Axon, enabling real-time, deduplicated data flow into EHRs.
Behavioral & women’s health partnerships
- Eleos Health + Google Cloud launched Polaris AI, a behavioral health foundational model.
- Transcarent expanded partnerships with Maven Clinic, Midi Health, and Progyny, building a one-stop women’s health platform for fertility, menopause, and family building.
- Oscar Health + Elektra Health announced HelloMeno, the first individual market plan dedicated to perimenopause and menopause care.
Report launch
Menlo Ventures’ 2025 The State of AI in Healthcare report
At HLTH 2025, Menlo Ventures released its inaugural report titled “2025: The State of AI in Healthcare”.
The report paints a clear picture of how quickly AI is becoming mainstream in healthcare:
AI adoption is accelerating: Healthcare organizations are now deploying AI 2.2× faster than other industries.
Domain-specific AI on the rise: 22% of healthcare organizations have implemented specialized AI tools. A 7× jump from 2024.
Spending surge: AI spending in healthcare hit $1.4 billion this year.
Startups lead the charge: 85% of generative AI investment is going to startups, not incumbents, signaling where innovation is truly happening.
Awards and recognition at HLTH 2025
The Digital Health 50
Ellen Knapp from CB Insights unveiled the Digital Health 50, honoring innovators pushing early detection, predictive analytics, and voice-assisted care.
The Digital Health Hub Foundation Awards
The Digital Health Awards recognized outstanding achievements across key healthcare categories, awarding both Best in Class and Rising Star distinctions.
HLTH USA 2025 startup pitch tournament
The Startup Pitch Tournament celebrated groundbreaking startups leading innovation across various healthcare sectors.
The Grand Finale Winner for the entire tournament was Veera.
National Institutes of Health’s (NIH) Neuromod Prize Winners
NIH announced the winners of its $9.8 Mn Neuromod Prize to advance targeted neuromodulation therapies.
- 1st Place ($3 Mn): University of Pittsburgh Department of Urology, for a multichannel implant to treat bladder, bowel, and sexual disorders.
- 2nd Place ($1.6 Mn): Juniper Biomedical, for a micro-implant to treat urinary and fecal incontinence.
Best in KLAS Research Emerging Solutions Top 20 Award
HLTH spotlighted the Best in KLAS Emerging Solutions Top 20.
The companies that healthcare leaders have recognized as most capable of advancing the Quadruple Aim. This includes elevating care quality, patient satisfaction, and staff well-being while cutting costs.
Wrapping up
HLTH USA 2025 wasn’t just a conference; it was a movement. An end to incrementalism.
A blueprint for AI that serves people, systems that support clinicians, and innovation that includes everyone.
The message from Las Vegas was clear: healthcare’s future isn’t about technology alone. It’s about co-creating a system built on empathy, equity, and evidence.
-By Alkama Sohail and the AHT Team
