Every year, CB Insights releases its highly anticipated AI 100 list, spotlighting the most promising emerging AI companies across the globe.
This annual roundup is a goldmine for investors, strategists, and tech enthusiasts alike. It offers a curated view of innovative startups reshaping industries from enterprise automation to generative AI.
But one sector in particular stands out in the 2025 edition: healthcare.
From generative agents for doctors to AI-powered maternal care and brain mapping, the list features a compelling group of startups that are reimagining how care is delivered, decisions are made, and lives are saved.
We went through the scouting report to spotlight 8 healthcare companies on the list you should know about.
8 most promising healthtech startups, per CB Insights
CB Insights’ platform evaluates these companies using real-time data, private funding intel, and their proprietary Mosaic Score—a metric that predicts a startup’s likelihood of success with 83% accuracy.
Here are the 8 health AI startups from this year’s CB Insights AI 100 list.
#1 Atropos Health
Headquarters: New York, USA
Founded: 2019 | Funding: $50M | Mosaic Score: 846/1000
Founders: Saurabh Gombar, Nigam Shah | CEO: Brigham Hyde
Atropos Health transforms healthcare decision-making through AI-powered real-world evidence (RWE). With partners like Stanford Health Care and Merck, Atropos offers rapid observational studies via tools like ChatRWD.
It’s growing fast with a 135% YoY (Year over Year) headcount increase and recent Series B funding aiming to bridge the gap between medical data and actionable clinical insights.
#2 Ambience Healthcare
Headquarters: San Francisco, USA
Founded: 2020 | Funding: $70M | Mosaic Score: 851/1000
Founders: Michael Ng, Nikhil Buduma
Ambience builds an AI operating system for healthcare documentation and clinical decision support. Backed by OpenAI Startup Fund and a16z, the company is growing rapidly with 159% YoY employee growth.
It has partnered with top health systems like Cleveland Clinic, helping reduce the admin burden for clinicians. It is aiming to become a core part of daily workflows.
#3 BrainSightAI
Headquarters: Bangalore, India
Founded: 2019 | Funding: $7M | Mosaic Score: 662/1000
Founders: Laina Emmanuel, Rimjhim Agrawal
This Indian startup creates AI-powered brain mapping tools for neurological and psychiatric diagnostics. It’s expanding beyond India and eyeing the U.S. market while working with global partners like Dassault Systèmes and Medidata.
BrainSightAI stands out amongst other startups for its focus on mental health and regulatory ambition.
#4 Clarium Health
Headquarters: New York, USA
Founded: 2020 | Funding: $38M | Mosaic Score: 636/1000
Founder: Steve Liou
Clarium’s Astra OS is revolutionizing healthcare logistics with an AI-based supply chain platform. Used by Yale New Haven Health and Geisinger, it delivers tangible results. Some clients reported $10M+ in annual savings.
With partnerships and Series A funding led by General Catalyst, Clarium is making hospitals more efficient and cost-effective.
#5 Delfina Care
Headquarters: San Francisco, USA
Founded: 2020 | Funding: $23M | Mosaic Score: 830/1000
Founder: Senan Ebrahim
Delfina focuses on AI for maternal health, reducing preterm births and gestational complications through early risk detection.
Its collaborations with public and private health systems aim to improve care in underserved communities, especially in high-risk regions like Texas. Backers include Mayo Clinic and UnitedHealthcare Accelerator.
#6 Ferrum Health
Headquarters: Sunnyvale, USA
Founded: 2017 | Funding: $31M | Mosaic Score: 780/1000
Founders: Pelu Tran, Kenneth Ko
Ferrum offers a secure AI deployment platform for hospitals, particularly in radiology. It partners with Sutter Health and Premier Radiology to reduce computing costs and speed up diagnostics.
The company addresses AI integration fatigue by making third-party clinical AI tools more accessible and easier to implement.
#7 Hippocratic AI
Headquarters: Palo Alto, USA
Founded: 2023 | Funding: $276M | Mosaic Score: 889/1000
Founder: Munjal Shah, Vishal Parikh, Meenesh Bhimani, Subho Mukherjee
One of the fastest-growing companies on the list, Hippocratic AI builds safety-focused, non-diagnostic generative AI agents for healthcare professionals.
With a $1.6B valuation in just two years and partnerships with Nvidia and Burjeel Holdings, it’s pushing the frontier of ethical, empathetic healthcare AI.
#8 Overjet: The dental AI
Headquarters: Boston, USA
Founded: 2018 | Funding: $131M | Mosaic Score: 856/1000
Founders: Wardah Inam, Alexander Jelicich, Deepak Ramaswamy
Overjet applies AI to dental diagnostics, helping enhance clinical care and speed up claims processing.
With regulatory clearances and adoption in major dental groups, it’s pioneering the use of AI in an often-overlooked corner of healthcare.
The bottom line
The global healthcare market was valued at a massive $21,222.5 billion in 2023, and it’s projected to more than double, reaching $44,760.73 billion by 2032 with a steady growth rate of 9.07% CAGR.
These 8 startups are pushing healthtech forward. Whether it’s reducing administrative overload, improving mental health diagnostics, or preventing preterm births, each of these companies is tackling a different pain point with purpose-built AI.
Their collective presence on CB Insights’ AI 100 list shows that healthtech is no longer just about future potential. It’s delivering real-world impact today.
As the $21 trillion global healthcare market gears up to double in size ($45 trillion by 2032) over the next decade, one thing is clear: AI won’t just be a part of that growth, it will help lead it.
These aren’t just startups to watch. They’re the future of healthcare in motion.
-By Rinkle Dudhani and the AHT Team
